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Folliculotropin (FSH) – meaning, action, deficiency, excess

30 stycznia 2023
Follicle-stimulating hormone, follicle-stimulating hormone, FSH, follicle-stimulating hormone deficiency, follicle-stimulating hormone excess
Folliculotropin is another of the hormones described by experts working with ONSEN® in response to requests from readers of the best blog about sleep.

As with almost any hormone, even the slightest disruption of folliculotropin levels can result in dysregulation of the entire endocrine system. It is on this system that our biopsychosocial functioning during the day depends, but also the possibility of a comfortable and regenerative sleep at night.

That is why it is so important to know not only what folliculotropin is, but also how it works. Thanks to this, it is possible to predict what the risk of a deficiency or excess of noradrenaline is, as well as to recognize possible disease symptoms early.
FSH, follicle-stimulating hormone, ovarian disorders, testicular hormones

Folliculotropin (FSH) – meaning

Follicle stimulating hormone (FSH), often also referred to as follicle stimulating hormone, is one of the most important tropic hormones. Produced in the pituitary gland, follicle stimulating hormone (FSH) has a peptide structure. Specifically, it is a glycoprotein made of 207 amino acids.
 
Follicultropin (FSH) has the greatest effect on sex hormones, as it is responsible for their synthesis. In women, its concentration affects the regulation of the menstrual cycle, as well as the stimulation of estrogen synthesis. In men, follicle stimulating hormone (FSH) affects spermatogenesis.

The action of follicle stimulating hormone (FSH) is closely related to estradiol (E2), which stimulates its production by feedback. It is also metabolized by the body and then excreted in the urine, which requires its continuous production to the extent necessary.

The norm of follicle stimulating hormone (FSH) in blood serum depends on sex, but also on the laboratory performing the test. In men, the norm of follicle stimulating hormone (FSH) is always between 4 mIU/ml and 25 mIU/ml. The norm of follicle stimulating hormone (FSH) is different in women.
  • In the follicular phase (the first phase of the menstrual cycle), the norm of follicle stimulating hormone (FSH) is below 12 mIU/ml;
  • In the ovulatory phase (between the first and second phase of the menstrual cycle), the norm of follicle stimulating hormone (FSH) ranged from 20 mIU/ml to 90 mIU/ml.
  • In the luteal phase (the second phase of the menstrual cycle) the norm of follicle stimulating hormone (FSH) is below 10 mIU/ml;
  • During pregnancy, follicle stimulating hormone (FSH) is undetectable or present in trace amounts.
  • During menopause, the normal follicle stimulating hormone (FSH) ranges from 40 mIU/ml to 250 mIU/ml.
Follicle-stimulating hormone, follicle-stimulating hormone, FSH, follicle-stimulating hormone deficiency, follicle-stimulating hormone excess

Folliculotropin (FSH) – action

Follicle stimulating hormone (FSH) is secreted continuously by the pituitary gland. It works together with lutropin, stimulating the maturation of Graff follicles and increasing the activity of aromatase. In men, it stimulates the growth of the seminal ducts, which leads to an increase in sperm production, as well as indirectly affects the effect of testosterone.

The effect of follicle stimulating hormone (FSH) is therefore primarily based on reproductive issues. However, follicle stimulating hormone (FSH) also affects changes in the endometrium in women and the proper functioning of the testicles in men. To a large extent, it depends on it the fertility of both sexes.

In addition, research is currently underway on the possibility of using modified follicle stimulating hormone (FSH) in the fight against cancers that have its receptors. If these tests are successful, it will be a carrier of drugs for targeted therapies.

It is sometimes observed that follicle-stimulating hormone (FSH) can affect human behavior and, consequently, also biopsychosocial functioning by affecting sex hormones. Its concentration deviating from the norm may result in serious changes in the state of health.
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Folliculotropin (FSH) – deficiency

Follicle-stimulating hormone (FSH) deficiency can be associated with problems with the pituitary gland, where it is produced, as well as other glands. The most commonly reported causes of follicle stimulating hormone (FSH) deficiency are:
  • tumors - especially of the pituitary gland;
  • pituitary insufficiency;
  • secondary ovarian failure;
  • secondary testicular failure;
  • bulimia;
  • anorexia.
Persistently low levels of follicle stimulating hormone (FSH) in the blood are not indicated. The most commonly noted effects of follicle stimulating hormone (FSH) deficiency are:
  • sterility;
  • impotence;
  • menstrual disorders;
  • puberty delay;
  • mood disorders;
  • sleep disorders.
Follicle-stimulating hormone, FSH, ovarian insufficiency, testicular insufficiency, chemotherapy, radiotherapy, menopause

Folliculotropin (FSH) – excess

Excess follicle-stimulating hormone (FSH) is most often associated with ailments of the pituitary gland, where it is produced, as well as other glands. The most common causes of excess follicle stimulating hormone (FSH) are:
  • tumors - especially of the pituitary gland;
  • overactive pituitary gland;
  • primary ovarian failure;
  • primary testicular failure;
  • chemotherapy;
  • radiotherapy.
Persistently high levels of cortisol in the blood are not indicated. The most commonly noted effects of excess follicle stimulating hormone (FSH) are:
  • weight loss;
  • premature puberty;
  • mood disorders;
  • sleep disorders.
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Folliculotropin (FSH) – sleep comfort

Mateusz Nesterok, M.Sc., a health and rehabilitation psychologist cooperating with ONSEN®, points out that there is no scientific evidence that the concentration of follicle stimulating hormone (FSH) has a direct impact on mental health. However, its excess or deficiency may be secondary and be related to the course of the disease that may have this effect. Hence, in the case of difficulties related to the level of follicle stimulating hormone (FSH).

As evidenced by the results of scientific research, the concentration of follicle stimulating hormone (FSH) in the blood does not directly affect the amount of sleep and its phase. However, any change in the level of one hormone usually causes a change in the concentration of another hormone. Thus, it is very likely that changes in the amount of follicle stimulating hormone (FSH) in the blood may indirectly affect the quality of sleep.

Maintaining the optimal level of follicle stimulating hormone (FSH) in the blood is conducive to a comfortable, healthy sleep. This, in turn, requires a functional mattress that provides perfect support for the body and spine. Maintaining the physiological curves of the spine during sleep, as well as allowing the body to fully relax, has a beneficial effect on all its systems, including the endocrine system.

ONSEN® offers the Osaka Air mattress, which is the most functional mattress available on the market. Its jobs to be done are to meet the users' needs and to effectively solve problems they may have. Thanks to this, it has become a cult product that fulfills all 10 basic mattress functionalities and allows for comfortable and healthy sleep. Moreover, like all ONSEN® products, the mattress is covered by even a 15-year warranty, as well as a program allowing for return within 100 days, minimizing the purchase risk to zero.

We also encourage you to explore other articles on the best sleep and health blog, as well as the Encyclopedia of Healthy Sleep prepared by the ONSEN® team of specialists. For those who care about spine health, we recommend a set of spine exercises prepared by our physiotherapist.
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FAQ: Folliculotropin (FSH)

What is follicle stimulating hormone (FSH) responsible for?

Follicle stimulating hormone (FSH) is responsible for the synthesis of sex hormones. The role of follicle stimulating hormone (FSH) is to regulate the menstrual cycle and spermatogenesis. The production of follicle-stimulating hormone (FSH) is based on feedback with estradiol (E2).

What are the effects of deficiency or low follicle stimulating hormone (FSH) levels?

The primary effect of follicle stimulating hormone (FSH) deficiency or low levels is infertility and impotence. In addition, follicle stimulating hormone (FSH) deficiency affects menstrual disorders. Low levels of follicle stimulating hormone (FSH) can lead to delayed puberty.

What are the effects of excess or high follicle stimulating hormone (FSH) levels?

The primary effect of excess or high levels of follicle stimulating hormone (FSH) is premature puberty. In addition, excess follicle stimulating hormone (FSH) can cause weight loss.

How to increase the secretion of follicle stimulating hormone (FSH)?

The secretion of follicle stimulating hormone (FSH) can be increased by administering pharmacological agents based on the recommendations of a specialist doctor. Incorrect blood levels require endocrinological consultation.

How to reduce the secretion of follicle stimulating hormone (FSH)?

The secretion of follicle stimulating hormone (FSH) can be reduced by administering pharmacological agents based on the recommendations of a specialist doctor. Incorrect blood levels require endocrinological consultation.

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