There are also
other factors that influence the development of myotonia, especially in its
hypocalcemic form, also known as overt myotonia, which involves
calcium deficiency. It occurs alongside the latent form, also known as
spasmophilia, which is generally characterized by insufficient
potassium and magnesium levels in the patient's blood.
A crucial
cause of myotonia is hormonal imbalance. Disturbances in the parathyroid glands' function, which can result from the
removal of the parathyroids during surgery or due to any
autoimmune diseases that lead to the disruption of
parathormone secretion, can lead to calcium deficiency in the blood.
Parathormone is the hormone responsible for regulating blood calcium levels by affecting the
bones, kidneys, and intestines, so its absence can significantly disturb the
calcium balance in the body.
Furthermore, a deficiency in calcium and vitamin D, essential for the proper functioning of the
skeletal and nervous systems, may result from impaired absorption of these substances in the digestive tract. This phenomenon can be the result of various gastrointestinal disorders such as
celiac disease or Crohn's disease, which significantly affect the intestines' ability to
absorb nutrients.
It can also be induced by
radiotherapy used as a form of cancer treatment, especially in the
neck area, which can lead to significant damage to
tissues and organs in that region. Once again, damage to the
parathyroid glands or other structures can disrupt the calcium balance and contribute to the development of myotonia.
A common cause of myotonia is the
loss of electrolytes from the body. The use of strong diuretic medications can lead to excessive
elimination of electrolytes from the body, including calcium. This, in turn, can result in an
electrolyte imbalance and hypocalcemia, which is a characteristic symptom of overt myotonia. The same mechanism can occur in
latent myotonia, which can even be triggered by prolonged consumption of
coffee or tea.
It's worth noting that the
kidneys play a crucial role in regulating blood
calcium levels by controlling its excretion. Disorders in
kidney function, such as chronic kidney failure, can lead to increased
loss of calcium from the body, which can worsen myotonia symptoms. This also applies to
magnesium and potassium, deficiencies of which can lead to spasmophilia.