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Tetany – symptoms, causes, treatment

26 listopada 2021
Tetany, calcium deficiency, hypocalcemia, mattresses
As we can easily see, modern medicine presents us with numerous challenges, and one of them is the understanding, diagnosis, and treatment of diseases, including neurodegenerative ones. One serious condition that poses a significant challenge for both patients and medical professionals is myotonia, also known as myotonic dystrophy. This rare disease affects muscle functions and the nervous system, introducing significant difficulties in daily functioning.

In this article, our experienced psychologist, Mr. Mateusz Nesterok, takes an in-depth look at the phenomenon of myotonia, focusing very closely on its symptoms, causes, and available treatment strategies. This condition, though rare, has a tremendous impact on the lives of patients and their families. Therefore, it is essential to understand its nature and the possibilities for assistance for individuals affected by this disease. This understanding allows us to better comprehend this unique condition and the measures that can be taken to improve the quality of life for patients.
Causes of tetany, tetany symptoms, mattresses

What are the symptoms of tetany?

One of the most prominent symptoms of myotonia is the gradual weakening of muscles and muscle tremors. Initially, this may manifest as difficulties in performing simple tasks such as getting up from a chair or climbing stairs. As the disease progresses, individuals with myotonia become increasingly dependent on the assistance of others in performing daily activities.

Myotonia affects the precision of movements, leading some individuals to have difficulty with gestures and actions that were once simple. Patients may struggle with holding objects, often dropping things, and may also have trouble with dressing or eating.

Muscle tremors, especially in the hands and legs, are another characteristic symptom of myotonia. This tremor may be mild at first, but it can intensify over time, leading to a loss of control over movements. Everyday activities such as eating with a spoon become challenging.

Myotonia can affect speech articulation, resulting in difficulties in pronouncing words and understanding others' speech. Patients may sometimes experience dysarthria, which is difficulty articulating sounds, significantly impairing communication. As the disease progresses, it may affect cognitive functions such as memory and thinking. Patients may have difficulty concentrating and remembering information as well as solving everyday problems.

The variety of myotonia symptoms can sometimes make diagnosis complicated. However, early identification and treatment can significantly impact the quality of life for patients. Therefore, individuals experiencing symptoms of myotonia should seek immediate help from a specialist who can assist in diagnosis and management of this challenging disease.
Tetany, magnesium deficiency, hypomagnesemia, mattresses

What are the causes of tetany?

As the latest advancements in medical research show, a cause of myotonia can be a mutation in the TDP-43 gene, which encodes a protein with the same name. This protein plays a significant role in human organisms, assisting in the regulation of gene expression and RNA stabilization. In the case of myotonia, there is, however, abnormal accumulation of the TDP-43 protein in neurons and muscles. This accumulation of abnormal proteins leads to damage to nerve and muscle tissues, which is characteristic of this disease. It is also observed in individuals with amyotrophic lateral sclerosis and frontotemporal dementia.

Modifications to this gene are inherited in an autosomal recessive manner, meaning that both parents must be carriers of the mutated gene, and the child must inherit two copies of this mutated gene, one from each parent. Parents carrying myotonia gene mutations are typically healthy and do not exhibit symptoms of the disease because the disease only manifests when both copies of the TDP-43 gene are altered.

There are numerous mutations in the TDP-43 gene that can lead to the development of myotonia and other diseases, making diagnosis and treatment more complex. However, the development of genetic medicine allows for increasingly precise genetic studies that can aid in identifying specific mutations for personalized therapy.
Myotonia was performed in two cases: overt and occult.
There are also other factors that influence the development of myotonia, especially in its hypocalcemic form, also known as overt myotonia, which involves calcium deficiency. It occurs alongside the latent form, also known as spasmophilia, which is generally characterized by insufficient potassium and magnesium levels in the patient's blood.

A crucial cause of myotonia is hormonal imbalance. Disturbances in the parathyroid glands' function, which can result from the removal of the parathyroids during surgery or due to any autoimmune diseases that lead to the disruption of parathormone secretion, can lead to calcium deficiency in the blood. Parathormone is the hormone responsible for regulating blood calcium levels by affecting the bones, kidneys, and intestines, so its absence can significantly disturb the calcium balance in the body.

Furthermore, a deficiency in calcium and vitamin D, essential for the proper functioning of the skeletal and nervous systems, may result from impaired absorption of these substances in the digestive tract. This phenomenon can be the result of various gastrointestinal disorders such as celiac disease or Crohn's disease, which significantly affect the intestines' ability to absorb nutrients.

It can also be induced by radiotherapy used as a form of cancer treatment, especially in the neck area, which can lead to significant damage to tissues and organs in that region. Once again, damage to the parathyroid glands or other structures can disrupt the calcium balance and contribute to the development of myotonia.

A common cause of myotonia is the loss of electrolytes from the body. The use of strong diuretic medications can lead to excessive elimination of electrolytes from the body, including calcium. This, in turn, can result in an electrolyte imbalance and hypocalcemia, which is a characteristic symptom of overt myotonia. The same mechanism can occur in latent myotonia, which can even be triggered by prolonged consumption of coffee or tea.

It's worth noting that the kidneys play a crucial role in regulating blood calcium levels by controlling its excretion. Disorders in kidney function, such as chronic kidney failure, can lead to increased loss of calcium from the body, which can worsen myotonia symptoms. This also applies to magnesium and potassium, deficiencies of which can lead to spasmophilia.
Treatment of tetany, tetany treatment, pillows

How is tetany treated?

Effective treatment of myotonia is based on identifying and eliminating specific trigger factors of the disease, especially in the hypocalcemic form. This means that the diagnosis and treatment must be tailored to individual needs, taking into account specific electrolyte disturbances.

If test results indicate a deficiency of calcium, magnesium, or other electrolytes, the treatment involves supplementing them through appropriate supplements or dietary changes. Regular monitoring of the levels of these substances in the blood is crucial to adjust the therapy to the patient's current needs. For this purpose, patients are given solutions of calcium and magnesium to alleviate symptoms and restore the proper level of these electrolytes in the body. This approach primarily aims to relieve muscle pain, spasms, and other symptoms associated with myotonia.

Preventing myotonia attacks primarily involves regular intake of calcium or magnesium, vitamin D, or vitamin B6, which help maintain the proper level of these substances in the blood. It is precisely the monitoring and adjusting of doses of these supplements to the individual needs of the patient that is crucial in preventing myotonia relapses.

It is also important to remember that patients with myotonia should regularly consult with a specialist doctor who will monitor their health and the levels of electrolytes in their blood to adjust the therapy and, thereby, ensure the highest quality of life and minimize the risk of myotonia attacks.

Tetany, potassium deficiency, hypokalemia, mattresses

Does tetany affect sleep?

Although the main symptoms of this disease are related to muscle and neurological disorders, myotonia can also have an impact on patients' sleep, introducing certain changes and difficulties into their sleep cycle. Despite nighttime sleep difficulties, some myotonia patients may experience excessive daytime sleepiness. This may be related to general fatigue resulting from dealing with the symptoms of the disease and continuous muscle tension experienced by some myotonia patients.

Many individuals affected by myotonia experience difficulties falling asleep, leading to insomnia. This phenomenon may be associated with muscle pain and discomfort, which are common symptoms of this disease. Nocturnal muscle spasms can also disrupt peaceful sleep. Myotonia is often associated with seizure-like episodes that may occur at night. These can be painful and disrupt sleep, leading to sleep disturbances and a decrease in sleep quality.

The treatment of myotonia can also affect patients' sleep. Taking certain medications, especially antiepileptic and analgesic drugs, may have side effects that affect sleep. Some of these medications may cause daytime drowsiness or lead to changes in sleep patterns. Therefore, it is important for myotonia patients to have access to medical and psychological support in managing their sleep.

It is worth emphasizing that the impact of myotonia on sleep is a complex issue and may vary depending on individual symptoms and needs of patients. In any case, it is essential to take care of sleep hygiene, including choosing a suitable and comfortable mattress and a comfortable pillow with an anatomical shape.

We also encourage you to explore other articles on the best sleep and health blog, as well as the Encyclopedia of Healthy Sleep prepared by the ONSEN® team of specialists. For those who care about spine health, we recommend a set of spine exercises prepared by our physiotherapist.
Mattress for the sick, hospital mattresses, orthopedic equipment

FAQ: Tetany

What is tetany?

Tetany is not so much a disease as a symptom characterized by uncontrolled, painful muscle contractions. The main cause of tetany is electrolyte imbalances, particularly a deficiency of calcium, magnesium, or potassium.

What are the symptoms of tetany?

Symptoms of tetany include gradual muscle weakness, which may initially manifest as difficulty in performing daily activities such as rising from a chair or climbing stairs. As the disease progresses, patients become increasingly dependent on the assistance of others to perform these tasks.

How to check if you have tetany?

The most sensitive and best test for detecting neuromuscular hyperexcitability, and therefore tetany, is electromyographic examination (EMG), also known as the tetany test. Additionally, blood tests for calcium, potassium, and magnesium levels can provide important information about tetany.

How to differentiate tetany from anxiety disorders?

Distinguishing tetany from anxiety disorders can be challenging because some tetany symptoms, especially when combined with a tingling sensation in the face and limbs, may be misinterpreted as a panic attack, especially in the case of latent tetany. Latent tetany manifests covertly and non-specifically, often leading to its accidental diagnosis.

Can tetany be diagnosed from blood tests?

In the diagnosis of tetany, biochemical blood tests are used to assess the total calcium concentration, and sometimes ionized calcium, as well as magnesium, potassium, and parathormone levels. Furthermore, measuring the level of vitamin D in serum, especially its metabolite 25(OH)D, can also provide valuable information to support the diagnosis of tetany.

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